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Meet the Cast

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Nick

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Nick, best friend to Andrew, is the resident late-bloomer in a big hurry to grow up. His own insecurities seem to be exacerbated as Andrew seems to be already fully engrossed in puberty.

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Voiced by: Nick Kroll

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Andrew

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Andrew, best friend to Nick, is hit hard by puberty. In Season 1, he hilariously struggles to control his urges. In Season 2 he is tormented by shame.

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Voiced by: John Mulaney

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Jessi

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As if puberty isn't hard enough, Jessi also navigates her parent's divorce. Between her first period, bra shopping, and her Bat Mitzvah, Jessi is busy becoming a strong young woman.

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Voiced by: Jessi Klein

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Missy

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Missy is the more sheltered and nerdy of the bunch. For the first couple episodes, she and Andrew get together. In Season 2, Missy struggles with body image issues.

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Voiced by: Jenny Slate

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Jay

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Neglected son and the youngest of three brothers, Jay develops a mean case of intimacy issues along with a side of toxic masculinity. At the end of Season 2, he questions his sexuality. 

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Voiced by: Jason Mantzoukas

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Coach Steve

 

Man-child and virgin (until mid Season 1), Steve is the kids P.E. teacher who, despite being middle-aged, still has an aging hormone monster of his own. At one point, he is tasked with teaching sex ed but ends up learning from the kids.

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Voiced by: Nick Kroll

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Maury - Hormone Monster

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Vulgar, ruthless, and popping up at the worst times, Maury represents the puberty taking over Andrew's thoughts and actions. Maury is his own character, separate from Andrew's personality, yet a dominant force in his life.

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Voiced by: Nick Kroll

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Connie - Hormone Monstress

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Connie takes over in the lives of Jessi and Missy. Causing them to explore sexual urges and explode at their mothers, Connie represents what puberty does to them.

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Voiced by: Maya Rudolph

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Shame Wizard

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The Shame Wizard emerges in Season 2 as the enemy to the Hormone Monsters. The Shame Wizard causes the kids to feel shameful about their feelings and urges, often prompting self loathing and isolation.

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Voiced by: David Thewlis

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